Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.64 |
| ▸ | CA2 | P00918 | 8/20 | 0.64 |
| ▸ | CA9 | Q16790 | 8/20 | 0.64 |
| ▸ | CA12 | O43570 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948094 | 0.99 | CA1 (0.65) | CA1CA2CA9CA12LMNA | |
| SCHEMBL27395364 | 0.94 | CA1 (0.60) | CA1CA2CA9CA12LMNA | |
| SCHEMBL27531899 | 0.94 | CA1 (0.60) | CA1CA2CA9CA12LMNA | |
| SCHEMBL27396057 | 0.92 | CA1 (0.62) | CA1CA2CA9CA12LMNA | |
| SCHEMBL5258409 | 0.86 | CA1 (0.64) | CA1CA2CA9CA12LMNA | |
| SCHEMBL12369632 | 0.84 | CA1 (0.68) | CA1CA2CA9CA12LMNA | |
| SCHEMBL28927348 | 0.83 | LMNA (0.76) | CA1CA2CA9CA12LMNA | |
| SCHEMBL15312909 | 0.81 | CA1 (0.76) | CA1CA2CA9CA12LMNA | |
| SCHEMBL15312834 | 0.80 | CA1 (0.64) | CA1CA2CA9CA12LMNA | |
| SCHEMBL5258405 | 0.80 | CA1 (0.64) | CA1CA2CA9CA12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255495-B1 | KILLING HYPOXIC TUMOR CELLS AND TREATING DERMATOLOGICAL DISEASES IN WARM-BLOODED ANIMALS VIA ADMINISTERING RADIOSENSITIZING AMOUNT OF ELECTRON-AFFINIC-DIAMINE | FLORIDA STATE UNIVERSITY | 2001-07-03 | — | — | US | disclosed |