SCHEMBL7941999

SCHEMBL7941999

CCCCCCCc1ccc(-c2ccc(C(=O)Oc3ccc(CCCCC)cc3F)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 11/20 0.57
RARA P10276 2/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 1/20 0.57
MTOR P42345 1/20 0.57
RARG P13631 1/20 0.56
THRA P10827 5/20 0.48
THRB P10828 5/20 0.48
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9477837 1.00 RARB (0.57) RARBRARAMAPTMEN1KMT2A
SCHEMBL10952232 0.94 RARB (0.50) RARBRARAMAPTMEN1KMT2A
SCHEMBL9640317 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9640149 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9641141 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9641076 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9641185 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9640326 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9641456 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A
SCHEMBL9641559 0.91 RARB (0.53) RARBRARAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US disclosed
EP-0317587-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1992-01-02 EP disclosed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP disclosed
US-5055224-A LIQUID CRYSTAL PHASE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US disclosed
EP-0317587-A1 LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1989-05-31 EP disclosed
WO-1988009360-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-12-01 WO disclosed
EP-0285617-A1 LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1988-10-12 EP disclosed
WO-1988002018-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-03-24 WO disclosed
WO-1986002375-A1 LIQUID CRYSTAL COMPOSITION MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-04-24 WO disclosed