Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 14/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 7/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 10/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | PRKCG | P05129 | 2/20 | 0.45 |
| ▸ | PRKCB | P05771 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
| ▸ | PRKCH | P24723 | 2/20 | 0.45 |
| ▸ | PRKCI | P41743 | 2/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815607 | 0.98 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL4622214 | 0.87 | PRKD3 (0.54) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL19164287 | 0.85 | CHRM2 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL7945723 | 0.85 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL10903569 | 0.84 | PRKD3 (0.46) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL2186329 | 0.84 | PRKD3 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL2183757 | 0.84 | PRKD3 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL7934828 | 0.84 | PRKD3 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL7941296 | 0.84 | PRKD3 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL7944299 | 0.84 | PRKD3 (0.59) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817270-B1 | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | GCP APPLIED TECH INC (US) | 2024-12-18 | — | — | EP | claimed |
| US-20150065614-A1 | Functionalized Polyamines For Clay Mitigation | SNF S.A.S. (FR) | 2015-03-05 | — | — | US | claimed |
| EP-2817270-A1 | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | W.R. Grace & CO. - CONN. (US) | 2014-12-31 | — | — | EP | claimed |
| CN-104245619-A | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | GRACE W R & CO | 2014-12-24 | — | — | CN | claimed |
| CN-103638551-A | Preparation method for chitosan 6-OH immobilized cyclodextrin included tea tree oil thermo-sensitive hydrogel | BEIJING INST TECHNOLOGY | 2014-03-19 | — | — | CN | claimed |
| WO-2013124003-A1 | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | W R GRACE & CO.-CONN (US) | 2013-08-29 | — | — | WO | claimed |
| EP-2817270-B1 | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | GCP APPLIED TECH INC (US) | 2024-12-18 | — | — | EP | disclosed |
| US-9994483-B2 | Functionalized polyamines for clay mitigation | GCP APPLIED TECHNOLOGIES INC. (US) | 2018-06-12 | — | — | US | disclosed |
| US-9950953-B2 | Functionalized polyamines for clay mitigation | GCP APPLIED TECHNOLOGIES INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20180065889-A1 | Functionalized Polyamines For Clay Mitigation | GCP APPLIED TECH INC (US) | 2018-03-08 | — | — | US | disclosed |
| US-20150065614-A1 | Functionalized Polyamines For Clay Mitigation | SNF S.A.S. (FR) | 2015-03-05 | — | — | US | disclosed |
| EP-2817270-A1 | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | W.R. Grace & CO. - CONN. (US) | 2014-12-31 | — | — | EP | disclosed |
| CN-104245619-A | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | GRACE W R & CO | 2014-12-24 | — | — | CN | disclosed |
| CN-103638551-A | Preparation method for chitosan 6-OH immobilized cyclodextrin included tea tree oil thermo-sensitive hydrogel | BEIJING INST TECHNOLOGY | 2014-03-19 | — | — | CN | disclosed |
| WO-2013124003-A1 | FUNCTIONALIZED POLYAMINES FOR CLAY MITIGATION | W R GRACE & CO.-CONN (US) | 2013-08-29 | — | — | WO | disclosed |
| US-6251379-B1 | KERATOSE WITH QUATERNARY AMMONIUM SALT AND SILICONE DERIVATIVES | SHISEIDO CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| US-4106903-A | IMPREGNATION WITH QUATERNARY AMMONIUM EPOXIDE FIXING AGENT AND WITH ADHESIVE, FIXING | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |