Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 4/20 | 0.41 |
| ▸ | EDNRB | P24530 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7534434 | 0.87 | PTGS2 (0.43) | PTGS2 | |
| SCHEMBL7534280 | 0.86 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL7533246 | 0.84 | FABP7 (0.54) | EDNRAEDNRB | |
| SCHEMBL7533335 | 0.80 | MEN1 (0.47) | PTGS2EDNRAEDNRB | |
| SCHEMBL7531484 | 0.80 | EDNRA (0.56) | EDNRAEDNRB | |
| SCHEMBL7531670 | 0.78 | FABP7 (0.49) | EDNRAEDNRB | |
| SCHEMBL8174959 | 0.73 | PTGS2 (0.41) | PTGS2EDNRAEDNRB | |
| SCHEMBL8625505 | 0.72 | PRKCI (0.47) | TP53 | |
| SCHEMBL9204054 | 0.72 | EDNRB (0.44) | PTGS2EDNRAEDNRB | |
| SCHEMBL8678051 | 0.72 | EDNRA (0.52) | EDNRAEDNRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271399-B1 | METHYL 3-(3,4-METHYLENEDIOXYPHENYL)-6-(PROP-1-YLOXY)-INDANE-2-CARBOXYLATE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION | 2001-08-07 | — | — | US | disclosed |