Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018567 | 0.64 | ALDH1A1 (0.61) | PDPK1ALDH1A1ATMPOLBNPC1 | |
| SCHEMBL2213286 | 0.62 | ALDH1A1 (0.59) | PDPK1ALDH1A1ATMPOLBNPC1 | |
| Biphenyl SCHEMBL8502577 | 0.59 | ALDH1A1 (0.82) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL25263755 | 0.58 | ATM (0.72) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL2548048 | 0.58 | ALDH1A1 (1.00) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL4002609 | 0.58 | ALDH1A1 (1.00) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL164 | 0.58 | ALDH1A1 (1.00) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL1358618 | 0.58 | ALDH1A1 (1.00) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29560186 | 0.58 | ALDH1A1 (1.00) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30108088 | 0.58 | ALDH1A1 (1.00) | ALDH1A1ATMNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371759-B2 | HMG-CoA reductase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-13 | — | — | US | disclosed |
| US-7371759-B2 | HMG-CoA reductase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-13 | — | — | US | disclosed |
| US-6245788-B1 | USING 5-ARYL-1,2,4-TRIADAZOL-3-YL (THIO)UREA COMPOUND | THE PROCTER & GAMBLE COMPANY | 2001-06-12 | — | — | US | disclosed |
| US-4689335-A | Heterocyclic guanidines for treating gastrointestinal motility dysfunction | WILLIAM H. RORER, INC. (US) | 1987-08-25 | — | — | US | disclosed |