SCHEMBL7942934

SCHEMBL7942934

CC(C)(C)c1cc(CCC(=O)N(CCO)C(C)(C)C)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
IAPP P10997 3/20 0.38
GAA P10253 3/20 0.37
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37
CYP2C9 P11712 1/20 0.37
MIF P14174 1/20 0.37
TYR P14679 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943146 0.86 CDK8 (0.41) HTTKMT2AHSP90AA1HSP90AB1ALDH1A1
SCHEMBL7933599 0.85 ALDH1A1 (0.52) HTTKMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL7943239 0.84 HSP90AA1 (0.51) HTTKMT2AL3MBTL1HSP90AA1HSP90AB1
SCHEMBL7941357 0.81 GAA (0.45) HTTKMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL7933818 0.81 HSP90AA1 (0.45) HTTKMT2AMEN1L3MBTL1HSP90AA1
SCHEMBL5137796 0.80 GAA (0.48) HTTKMT2AMEN1HSP90AA1HSP90AB1
SCHEMBL7943216 0.80 GAA (0.40) HTTKMT2AMEN1L3MBTL1HSP90AA1
SCHEMBL7944806 0.79 HSP90AA1 (0.43) HTTKMT2AMEN1L3MBTL1HSP90AA1
SCHEMBL7933554 0.78 HSP90AA1 (0.41) HTTKMT2AMEN1HSP90AA1HSP90AB1
SCHEMBL7944867 0.77 HSP90AA1 (0.40) HTTKMT2AMEN1L3MBTL1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-6075159-A USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-13 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed