Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 4/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635425 | 0.78 | HPRT1 (0.50) | CYP1A2CYP2A6ALDH1A1HIF1AHPGD | |
| SCHEMBL4035804 | 0.77 | CYP2A6 (0.36) | CYP1A2CYP2A6ALDH1A1HPGDTDP1 | |
| SCHEMBL30477217 | 0.77 | CYP2A6 (0.36) | CYP1A2CYP2A6ALDH1A1HPGDTDP1 | |
| SCHEMBL1822675 | 0.74 | KDM4E (0.43) | CYP1A2CYP2A6ALDH1A1HIF1AHPGD | |
| SCHEMBL29481537 | 0.74 | KDM4E (0.43) | CYP1A2CYP2A6ALDH1A1HIF1AHPGD | |
| Lithium SCHEMBL29773580 | 0.73 | KDM4E (0.42) | CYP1A2CYP2A6ALDH1A1HIF1AHPGD | |
| SCHEMBL599477 | 0.71 | CYP1A2 (0.87) | CYP1A2CYP2A6ALDH1A1TYMSHIF1A | |
| SCHEMBL6705797 | 0.71 | CYP1A2 (0.87) | CYP1A2CYP2A6ALDH1A1TYMSHIF1A | |
| SCHEMBL424167 | 0.71 | CYP1A2 (1.00) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL29463284 | 0.71 | CYP1A2 (1.00) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297333-B1 | METALLOCENE TRANSITION METAL COMPOUND HAVING AN INDENYL GROUP AND A FLUORENYL GROUP AS LIGANDS, SPECIFIC SUBSTITUENT ON A SPECIFIC POSITION OF THE INDENYL GROUP GIVES HIGH MOLECULAR WEIGHT AND HIGH ACTIVITY | MITSUI CHEMICALS INC (JP) | 2001-10-02 | — | — | US | disclosed |
| US-6004897-A | TRANSITION METAL INDENE-FLUORINE COMPLEX COORDINATION CATALYST WITH ORGANOALUMINUM AND ALUMOXANE COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0754698-A2 | An olefin polymerization catalyst and a process for preparing olefin polymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |