Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 18/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951579 | 0.90 | ANO1 (0.56) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL12830907 | 0.84 | ANO1 (0.37) | ANO1MEN1KMT2A | |
| SCHEMBL1954030 | 0.81 | ANO1 (0.63) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1953124 | 0.77 | ANO1 (0.57) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1907652 | 0.77 | ANO1 (0.57) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1951883 | 0.77 | ANO1 (0.57) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL12756759 | 0.76 | NPY5R (0.41) | ANO1MEN1KMT2A | |
| SCHEMBL1908451 | 0.75 | ANO1 (0.56) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1954708 | 0.75 | ANO1 (0.56) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL13819661 | 0.74 | MEN1 (0.69) | ANO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |