Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 13/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756759 | 0.90 | NPY5R (0.41) | ANO1NPY5RHSP90AA1HSP90AB1MEN1 | |
| SCHEMBL7943197 | 0.84 | ANO1 (0.54) | ANO1MEN1KMT2A | |
| SCHEMBL12756737 | 0.81 | NPY5R (0.48) | ANO1NPY5RMEN1KMT2ATP53 | |
| SCHEMBL12756733 | 0.77 | P2RX7 (0.43) | ANO1NPY5RTP53MDM2 | |
| SCHEMBL1951579 | 0.76 | ANO1 (0.56) | ANO1MEN1KMT2A | |
| SCHEMBL12756744 | 0.74 | P2RX7 (0.40) | ANO1NPY5RMEN1KMT2ATP53 | |
| SCHEMBL12830909 | 0.73 | ANO1 (0.38) | ANO1NPY5RTP53MDM2 | |
| SCHEMBL12756892 | 0.73 | ANO1 (0.46) | ANO1MEN1KMT2A | |
| SCHEMBL12756752 | 0.72 | TAS1R3 (0.54) | MEN1KMT2A | |
| SCHEMBL12829854 | 0.72 | GAA (0.43) | ANO1NPY5RMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |