Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826225 | 1.00 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL31216393 | 0.95 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL29004140 | 0.95 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL11829645 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4TDP1POLB | |
| SCHEMBL28319879 | 0.90 | TSHR (0.57) | TSHRALDH1A1CYP3A4TDP1POLB | |
| SCHEMBL7912783 | 0.90 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL29580127 | 0.90 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL31589984 | 0.90 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL29110637 | 0.90 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL29581623 | 0.90 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777697-B1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-0987306-A2 | Curable silicon sealant/adhesive compositions. | LOCTITE CORPORATION (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0777697-A4 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 1998-08-19 | — | — | EP | disclosed |
| EP-0777697-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996039458-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |