Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940101 | 0.95 | SERPINE1 (0.51) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9246950 | 0.92 | ESR1 (0.58) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7944813 | 0.92 | ESR1 (0.58) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7943043 | 0.89 | LMNA (0.49) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL13840644 | 0.88 | ESR1 (0.66) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7759185 | 0.88 | ESR1 (0.50) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL7943202 | 0.87 | ESR1 (0.58) | ESR1SERPINE1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL439370 | 0.87 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5909518 | 0.87 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL539846 | 0.87 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0861847-A2 | Stabilizer composition and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |