SCHEMBL7943368

SCHEMBL7943368

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](Cl)(Cl)C1C(C)=Cc2c(-c3ccccc3)cccc21.[InH3]

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
CYP2A6 P11509 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31
ESR2 Q92731 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2525984 0.98 PDCD1 (0.33) PDCD1CD274CYP2A6ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL31386845 0.97 PDCD1 (0.33) PDCD1CD274CYP2A6ALDH1A1MAPK1
SCHEMBL6553568 0.94 PDCD1 (0.31) PDCD1CD274CYP2A6ALDH1A1MAPK1
SCHEMBL20496069 0.94 PDCD1 (0.31) PDCD1CD274CYP2A6ALDH1A1MAPK1
SCHEMBL21980379 0.93 PDCD1 (0.30) PDCD1CD274
SCHEMBL8633271 0.92
SCHEMBL7849130 0.92 PDCD1 (0.33) PDCD1CD274ESR2
SCHEMBL2520449 0.88
SCHEMBL8633284 0.88 CA12 (0.33) ALDH1A1
SCHEMBL8630713 0.88 PDCD1 (0.31) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001046201-A1 GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-06-28 WO disclosed