Sugi Predict

Sugi Predict / Compounds / SCHEMBL2525984

SCHEMBL2525984

SCHEMBL2525984

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](Cl)(Cl)C1C(C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDCD1 Q15116 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33
▸ CYP2A6 P11509 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ CHRNB2 P17787 1/20 0.32
▸ CHRNA4 P43681 1/20 0.32
▸ ESR2 Q92731 1/20 0.31
▸ BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7943368 0.98 PDCD1 (0.33) PDCD1CD274CYP2A6ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL31386845 0.98 PDCD1 (0.33) PDCD1CD274CYP2A6ALDH1A1MAPK1
SCHEMBL6553568 0.96 PDCD1 (0.31) PDCD1CD274CYP2A6ALDH1A1MAPK1
SCHEMBL20496069 0.96 PDCD1 (0.31) PDCD1CD274CYP2A6ALDH1A1MAPK1
SCHEMBL21980379 0.94 PDCD1 (0.30) PDCD1CD274
SCHEMBL8633271 0.93 — —
SCHEMBL7849130 0.93 PDCD1 (0.33) PDCD1CD274ESR2
SCHEMBL2520449 0.89 — —
SCHEMBL8633284 0.89 CA12 (0.33) ALDH1A1
SCHEMBL8630713 0.89 PDCD1 (0.31) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238026-B2 PIGMENT CONCENTRATES AND METHODS FOR PRODUCTION THEREOF BASF AG (DE) 2007-01-24 — — EP claimed
WO-2025033702-A1 HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED CATALYST, AND PREPARATION METHOD THEREOF 한화솔루션 주식회사 2025-02-13 — — WO disclosed
WO-2025033703-A1 HIGH-DENSITY ETHYLENE-BASED POLYMER USING HYBRID SUPPORTED CATALYST, AND PREPARATION METHOD THEREOF 한화솔루션 주식회사 2025-02-13 — — WO disclosed
US-11634513-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-04-25 — — US disclosed
US-20220242976-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2022-08-04 — — US disclosed
EP-2033975-B1 Catalyst composition BASELL POLYOLEFINE GMBH (DE) 2014-05-14 — — EP disclosed
US-8039569-B2 Polyethylene molding compositions for injection molding applications BASELL POLYOLEFINE GMBH (DE) 2011-10-18 — — US disclosed
EP-1874830-B1 MOLDING COMPOSITION COMPRISING POLYETHYLENE FOR PREPARING FILMS AND PROCESS FOR PREPARING THE MOLDING COMPOSITION IN THE PRESENCE OF A MIXED CATALYST BASELL POLYOLEFINE GMBH (DE) 2010-10-20 — — EP disclosed
US-20090311453-A1 Molding compostion comprsing polyethlene for preparing films and process for preparing the molding composition in the presence of a mixed catalyst BASELL POLYOLEFINE GMBH (DE) 2009-12-17 — — US disclosed
US-20090306324-A1 Polyethylene molding compositions for injection molding applications BASELL POLYOLEFINE GMBH (DE) 2009-12-10 — — US disclosed
WO-2006114209-A1 MOLDING COMPOSITION COMPRISING POLYETHYLENE FOR PREPARING FILMS AND PROCESS FOR PREPARING THE MOLDING COMPOSITION IN THE PRESENCE OF A MIXED CATALYST BASELL POLYOLEFINE GMBH (DE) 2006-11-02 — — WO disclosed
US-7038070-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2006-05-02 — — US disclosed
US-6963017-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2005-11-08 — — US disclosed
EP-0968158-B1 METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM BASELL POLYOLEFINE GMBH (DE) 2005-08-10 — — EP disclosed
US-20050033076-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2005-02-10 — — US disclosed
US-6812274-B2 Pigment concentrates and their production BASF AKTIENGESELLSCHAFT (DE) 2004-11-02 — — US disclosed
US-20030019400-A1 Pigment concentrates and method for production thereof BASF AKTIENGESELLSHCAFT (DE) 2003-01-30 — — US disclosed
US-20030009046-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2003-01-09 — — US disclosed
EP-1153044-A1 FUNCTIONALIZED ETHYLENE/VINYL OR VINYLIDENE AROMATIC INTERPOLYMERS THE DOW CHEMICAL COMPANY (US) 2001-11-14 — — EP disclosed
WO-2000046258-A1 FUNCTIONALIZED ETHYLENE/VINYL OR VINYLIDENE AROMATIC INTERPOLYMERS THE DOW CHEMICAL COMPANY (US) 2000-08-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090311453-A1 Molding compostion comprsing polyethlene for preparing films and process for preparing the molding composition in the presence of a mixed catalyst MAFG, PARG, MICOS13 PDCD1 4355/4885CD274 4020/4885CYP2A6 3031/4885
US-20050033076-A1 Preparation of preparing substituted indanones CYP1A2, CYP2J2, IDH3A PDCD1 2476/4885CD274 3121/4885CYP2A6 64/4885
US-20030009046-A1 Preparation of preparing substituted indanones CYP1A2, CYP1B1, CYP1A1 PDCD1 2265/4885CD274 2659/4885CYP2A6 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.