Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944754 | 0.79 | BACE1 (0.51) | BACE1 | |
| SCHEMBL12301731 | 0.78 | BACE1 (0.48) | BACE1 | |
| SCHEMBL12301705 | 0.77 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL7943456 | 0.77 | BACE1 (0.49) | BACE1 | |
| SCHEMBL7944645 | 0.77 | BACE1 (0.61) | BACE1 | |
| SCHEMBL7945205 | 0.76 | BACE1 (0.61) | BACE1 | |
| SCHEMBL12445513 | 0.76 | BACE1 (0.58) | BACE1CTSD | |
| SCHEMBL7934657 | 0.75 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL7946585 | 0.75 | BACE1 (0.50) | BACE1 | |
| SCHEMBL12303332 | 0.75 | BACE1 (0.59) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010047372-A1 | 2-AMINOPYRIDIN-4-ONE AND 2-AMINOPYRIDINE DERIVATIVE BOTH HAVING BACE1-INHIBITING ACTIVITY | 塩野義製薬株式会社 (JP) | 2010-04-29 | — | — | WO | disclosed |