Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698866 | 0.85 | TSHR (0.43) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL13698867 | 0.85 | TSHR (0.43) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL15550819 | 0.83 | TSHR (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL6856406 | 0.82 | CYP1A2 (0.39) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL16111259 | 0.81 | TSHR (0.46) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL16111260 | 0.79 | TSHR (0.44) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL16110652 | 0.75 | TSHR (0.40) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL1502377 | 0.74 | CHRM1 (0.38) | TSHRCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL16110875 | 0.74 | TSHR (0.43) | TSHRKMT2AMEN1LMNACA12 | |
| SCHEMBL3375229 | 0.74 | CYP4F2 (0.33) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011824-A1 | NOVEL XANTHINE COMPOUNDS | CONCERT PHARMACEUTICALS, INC. (US) | 2010-01-28 | — | — | WO | disclosed |