Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 18/20 | 1.00 |
| ▸ | NQO2 | P16083 | 17/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956487 | 1.00 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7956485 | 0.93 | MTNR1A (0.87) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8887708 | 0.91 | MTNR1A (0.83) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7950293 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4685402 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7950319 | 0.87 | MTNR1A (0.82) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4685396 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4687318 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7943795 | 0.85 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL135600 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661186-A | MELATONERGIC EFFECT; CENTRAL NERVOUS SYSTEM DISODERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | claimed |
| EP-0728738-A1 | Tetralinyl- and indanyl-ethylamides having melatonergic activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-28 | — | — | EP | claimed |
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-B1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5661186-A | MELATONERGIC EFFECT; CENTRAL NERVOUS SYSTEM DISODERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0728738-A1 | Tetralinyl- and indanyl-ethylamides having melatonergic activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |