Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943769 | 1.00 | CYP19A1 (0.47) | CYP19A1CYP11B2ABCB1MAOBNQO2 | |
| SCHEMBL7951341 | 0.97 | CYP19A1 (0.47) | CYP19A1CYP11B2ABCB1MAOBNQO2 | |
| SCHEMBL7951337 | 0.97 | CYP19A1 (0.47) | CYP19A1CYP11B2ABCB1MAOBNQO2 | |
| SCHEMBL1688133 | 0.97 | CYP19A1 (0.47) | CYP19A1CYP11B2ABCB1MAOBNQO2 | |
| SCHEMBL4688568 | 0.91 | CYP19A1 (0.56) | CYP19A1CYP11B2MAOBNQO2MTNR1A | |
| SCHEMBL4688774 | 0.91 | CYP19A1 (0.56) | CYP19A1CYP11B2MAOBNQO2MTNR1A | |
| SCHEMBL31028072 | 0.91 | CYP19A1 (0.56) | CYP19A1CYP11B2MAOBNQO2MTNR1A | |
| SCHEMBL4688567 | 0.91 | CYP19A1 (0.56) | CYP19A1CYP11B2MAOBNQO2MTNR1A | |
| SCHEMBL7952133 | 0.85 | ADCY8 (0.36) | CYP19A1CYP11B2ABCB1MAOBNQO2 | |
| SCHEMBL7952131 | 0.85 | ADCY8 (0.36) | CYP19A1CYP11B2ABCB1MAOBNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |