SCHEMBL7943787

SCHEMBL7943787

OC=CCC1(CC=CO)CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
BLM P54132 1/20 0.32
CACNA2D1 P54289 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10773155 0.97
SCHEMBL14128903 0.77 USP2 (0.31) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL14128972 0.74 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL8248493 0.74 USP2 (0.32) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL7154813 0.70 CYP2C19 (0.52) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL862034 0.68 EPHX1 (0.35)
SCHEMBL14128919 0.67
SCHEMBL3961575 0.67 POLB (0.33) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL14128879 0.67 USP2 (0.34) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL3960623 0.67 POLB (0.33) USP2ALDH1A1LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US claimed
EP-3296283-B1 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES BASF SE (DE) 2021-06-16 EP disclosed
US-9981897-B2 Ethers of bis(hydroxymethyl)cyclohexanes BASF SE (DE) 2018-05-29 US disclosed
EP-3296283-A1 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES BASF SE (DE) 2018-03-21 EP disclosed
EP-2726450-B1 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES BASF SE (DE) 2017-12-06 EP disclosed
US-20160347698-A1 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES BASF SE (DE) 2016-12-01 US disclosed
US-9452962-B2 Ethers of bis(hydroxymethyl)cyclohexanes BASF SE (DE) 2016-09-27 US disclosed
US-20140296579-A1 ETHERS OF BIS (HYDROXYMETHYL) CYCLOHEXANES BASF SE (DE) 2014-10-02 US disclosed
EP-2726450-A2 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES BASF SE (DE) 2014-05-07 EP disclosed
WO-2013004579-A2 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES BASF SE (DE) 2013-01-10 WO disclosed
US-4873079-A WITH COSOLVENTS CONSISTING OF BRANCHED CHAIN HYDROCARBON DIOLS AND BIS(HYDROXYALKYL) CYCLOALKENES; BETTER DYE TAKE CLAIROL INCORPORATED (US) 1989-10-10 US disclosed
WO-1989006228-A1 VINYL ETHER TERMINATED ESTER AND URETHANE RESINS FROM BIS(HYDROXYALKYL)CYCLOALKANES ALLIED-SIGNAL INC. (US) 1989-07-13 WO disclosed
US-4775732-A HIGH SPEED CURING ALLIED-SIGNAL INC. (US) 1988-10-04 US disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0063528-B1 CONDENSATION POLYMERIC PHOTOCONDUCTORS CONTAINING PENDANT ARYLAMINES, PHOTOCONDUCTIVE COMPOSITIONS AND ELECTROPHOTOGRAPHIC ELEMENTS CONTAINING THESE PHOTOCONDUCTORS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-08-19 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
US-4463078-A POLYESTER COATINGS AND FILMS; ELECTROGRAPHY; XEROGRAPHY; LIGHT SEN EASTMAN KODAK COMPANY (US) 1984-07-31 US disclosed
US-4395475-A Condensation polymeric photoconductors containing pendant arylamines EASTMAN KODAK COMPANY (US) 1983-07-26 US disclosed
EP-0063528-A2 Condensation polymeric photoconductors containing pendant arylamines, photoconductive compositions and electrophotographic elements containing these photoconductors EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-10-27 EP disclosed
US-4001153-A Unsaturated polyester resin composition TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160347698-A1 ETHERS OF BIS(HYDROXYMETHYL)CYCLOHEXANES CYP2E1, CYP1A1, CYP2S1 USP2 916/4885ALDH1A1 627/4885LMNA 2375/4885
US-20140296579-A1 ETHERS OF BIS (HYDROXYMETHYL) CYCLOHEXANES CYP2E1, CYP1A1, CYP2S1 USP2 916/4885ALDH1A1 627/4885LMNA 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.