Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943800 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL14065573 | 0.75 | RXRA (0.44) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31028056 | 0.75 | CYP19A1 (0.33) | SMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL7951405 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7951403 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL6783870 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7647664 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL6783536 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL31028060 | 0.68 | CYP19A1 (0.49) | ALDH1A1TYMS | |
| SCHEMBL31028079 | 0.68 | CYP19A1 (0.53) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235789-B1 | GLANDULAR DISORDERS; SLEEP DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0781271-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008466-A1 | BENZOCYCLOALKENE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-21 | — | — | WO | disclosed |