Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954475 | 0.84 | EDNRB (0.71) | EDNRBEDNRA | |
| SCHEMBL7943851 | 0.83 | EDNRB (0.76) | EDNRBEDNRA | |
| SCHEMBL7943804 | 0.82 | EDNRB (0.87) | EDNRBEDNRA | |
| SCHEMBL7956965 | 0.81 | EDNRB (0.78) | EDNRBEDNRA | |
| SCHEMBL7943809 | 0.80 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7952779 | 0.79 | EDNRB (0.95) | EDNRB | |
| SCHEMBL795073 | 0.79 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7950749 | 0.78 | EDNRB (0.73) | EDNRBEDNRA | |
| SCHEMBL7952334 | 0.77 | EDNRB (0.73) | EDNRB | |
| SCHEMBL7951952 | 0.77 | EDNRB (0.73) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| CN-1234029-A | Chromene-3-carboxylate derivative | SHIONOGI & CO (JP) | 1999-11-03 | — | — | CN | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |