Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956806 | 0.90 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7943851 | 0.87 | EDNRB (0.76) | EDNRBEDNRA | |
| SCHEMBL27561156 | 0.86 | EDNRB (0.61) | EDNRB | |
| SCHEMBL7943804 | 0.86 | EDNRB (0.87) | EDNRBEDNRA | |
| SCHEMBL27561155 | 0.86 | EDNRB (0.58) | EDNRBEDNRA | |
| SCHEMBL7954997 | 0.84 | EDNRB (0.57) | EDNRBEDNRA | |
| SCHEMBL7943835 | 0.84 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL7956965 | 0.84 | EDNRB (0.78) | EDNRBEDNRA | |
| SCHEMBL7943809 | 0.83 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL27934789 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103271904-A | Nitric oxide donor endothelin receptor antagonist as well as preparation method and application thereof | UNIV SOUTHEAST | 2013-09-04 | — | — | CN | disclosed |
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| CN-1234029-A | Chromene-3-carboxylate derivative | SHIONOGI & CO (JP) | 1999-11-03 | — | — | CN | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |