Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360475 | 0.93 | TDP1 (0.60) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL570920 | 0.93 | TDP1 (0.60) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL5166543 | 0.91 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1TSHRKMT2A | |
| Ammonia Solution, Strong SCHEMBL27753074 | 0.91 | TDP1 (0.59) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL28864124 | 0.91 | L3MBTL1 (0.59) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL29534771 | 0.89 | GPR17 (0.65) | GPR17TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL28289702 | 0.89 | GPR17 (0.65) | GPR17TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL40429 | 0.89 | GPR17 (0.65) | GPR17TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27386628 | 0.85 | TDP1 (0.54) | TDP1L3MBTL1ADRB2ADRB1ADRB3 | |
| SCHEMBL7467811 | 0.84 | TDP1 (0.52) | TDP1L3MBTL1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |