Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | GOT1 | P17174 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204354 | 0.86 | AHR (0.47) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL623364 | 0.86 | AHR (0.47) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL931526 | 0.84 | AHR (0.46) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL8230949 | 0.84 | AHR (0.46) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL30204500 | 0.84 | AHR (0.46) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL13799364 | 0.84 | AHR (0.46) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL6184160 | 0.83 | AHR (0.45) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL5791985 | 0.83 | AHR (0.45) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL19751042 | 0.82 | AHR (0.50) | AHRCMA1HTR1ADRD2HTR2A | |
| SCHEMBL623837 | 0.82 | HTR1A (0.46) | AHRCMA1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010566-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF ZIPRASIDONE | LUPIN LIMITED (IN) | 2010-01-28 | — | — | WO | disclosed |