Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 5/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349164 | 1.00 | PDE4B (0.47) | PDE4BPDE4AALDH1A1POLBF7 | |
| SCHEMBL7940588 | 0.92 | PDE4B (0.57) | PDE4BPDE4AALDH1A1POLBF7 | |
| SCHEMBL7359063 | 0.92 | PDE4B (0.57) | PDE4BPDE4AALDH1A1POLBF7 | |
| Hydrochloric Acid SCHEMBL7359060 | 0.91 | PDE4B (0.56) | PDE4BPDE4AALDH1A1POLBF7 | |
| Hydrochloric Acid SCHEMBL7359055 | 0.91 | PDE4B (0.56) | PDE4BPDE4AALDH1A1POLBF7 | |
| SCHEMBL7357603 | 0.84 | ALDH1A1 (0.42) | ALDH1A1POLBF7F3F10 | |
| SCHEMBL7357599 | 0.84 | ALDH1A1 (0.42) | ALDH1A1POLBF7F3F10 | |
| SCHEMBL7381984 | 0.83 | PDE4A (0.47) | PDE4BPDE4AALDH1A1POLBF7 | |
| SCHEMBL7381987 | 0.83 | PDE4A (0.47) | PDE4BPDE4AALDH1A1POLBF7 | |
| SCHEMBL7349224 | 0.82 | F7 (0.46) | PDE4BPDE4AALDH1A1POLBF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834508-B1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0834508-A1 | Substituted biphenyl or phenylpyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-08 | — | — | EP | disclosed |