Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 20/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.64 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.63 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293348 | 0.92 | SLC16A1 (0.65) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL14845838 | 0.90 | SLC16A1 (0.70) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL10292856 | 0.88 | SLC16A1 (0.68) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL5864717 | 0.80 | SLC16A1 (0.83) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL8144478 | 0.79 | SLC16A1 (0.75) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7935749 | 0.78 | SLC16A1 (0.48) | SLC16A1CYP2C9CYP3A4SLC16A3 | |
| SCHEMBL29818663 | 0.78 | SLC16A1 (1.00) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| Hydrochloric Acid SCHEMBL30148484 | 0.78 | SLC16A1 (1.00) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL7005642 | 0.76 | SLC16A1 (0.66) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 | |
| SCHEMBL7005454 | 0.75 | SLC16A1 (0.65) | SLC16A1CYP2C9CYP3A4SLC16A7SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249118-A1 | protein kinase modulators such as Propane-1-sulfonic acid [2,4-difluoro-3-(5-ethoxy-1H-pyrrolo[1,3-b]pyridine-3-carbonyl)-phenyl]-amide, used to regulate signal transduction cascades, involved in the control of physiological functions including cellular growth and proliferation; anticarcinogenic agents | PLEXXIKON INC. | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249118-A1 | protein kinase modulators such as Propane-1-sulfonic acid [2,4-difluoro-3-(5-ethoxy-1H-pyrrolo[1,3-b]pyridine-3-carbonyl)-phenyl]-amide, used to regulate signal transduction cascades, involved in the control of physiological functions including cellular growth and proliferation; anticarcinogenic agents | MAP4K1, MAP4K2, MAP3K1 | SLC16A1 4571/4885CYP2C9 4869/4885CYP3A4 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.