Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945499 | 0.93 | S1PR3 (0.56) | S1PR3TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7944138 | 0.93 | S1PR3 (0.56) | S1PR3TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6686085 | 0.88 | TSHR (0.43) | S1PR3TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8470113 | 0.81 | ALDH1A1 (0.39) | S1PR3TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6928648 | 0.81 | ALDH1A1 (0.39) | S1PR3TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL5173176 | 0.80 | S1PR3 (0.42) | S1PR3TSHRL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL1547662 | 0.77 | TSHR (0.51) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL6689572 | 0.76 | TSHR (0.44) | S1PR3TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13287325 | 0.76 | LCK (0.57) | TSHRCYP3A4MAPK1ESR1LMNA | |
| SCHEMBL11762395 | 0.75 | S1PR3 (0.44) | S1PR3ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191192-B1 | URETHRAL CATHETERS, GLOVES | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0887373-A2 | Antibacterial polymeric moldings | Toyo Boseki Kabushiki Kaisha (JP) | 1998-12-30 | — | — | EP | disclosed |