Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903340 | 0.85 | HDAC1 (0.41) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL1002924 | 0.83 | LMNA (0.39) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL14294336 | 0.79 | LMNA (0.52) | HDAC1HDAC8HDAC6LMNAKMT2A | |
| SCHEMBL1001407 | 0.78 | HDAC1 (0.42) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL1002194 | 0.77 | KDM5B (0.41) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL15802660 | 0.77 | KDM4E (0.42) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL1002193 | 0.77 | KDM5B (0.41) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL1004600 | 0.77 | KDM5B (0.41) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL1002137 | 0.77 | KDM5B (0.41) | MMP13HDAC1HDAC8HDAC6KDM5B | |
| SCHEMBL15520374 | 0.77 | KDM5B (0.41) | MMP13HDAC1HDAC8HDAC6KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017079-A1 | OXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | MERCK & CO., INC. (US) | 2010-02-11 | — | — | WO | disclosed |