Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008715 | 0.90 | TDP1 (0.49) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7997686 | 0.85 | KDM4E (0.46) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7996748 | 0.85 | CA12 (0.51) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8005875 | 0.85 | TDP1 (0.44) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL3660558 | 0.85 | TDP1 (0.44) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL3067373 | 0.84 | NOTUM (0.47) | NOTUMTDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL8005894 | 0.82 | SLC7A5 (0.43) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL17707305 | 0.81 | TDP1 (0.58) | TDP1MAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL2171295 | 0.81 | NOTUM (0.41) | NOTUMTDP1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL16203106 | 0.80 | TDP1 (0.55) | NOTUMTDP1MAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |