Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA7 | P43166 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008715 | 0.91 | TDP1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8005875 | 0.86 | TDP1 (0.44) | TDP1CNR2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL3660558 | 0.86 | TDP1 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7945903 | 0.85 | NOTUM (0.43) | TDP1CNR2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL7997686 | 0.84 | KDM4E (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8005894 | 0.83 | SLC7A5 (0.43) | TDP1CNR2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL17707305 | 0.82 | TDP1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1495802 | 0.80 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1495726 | 0.79 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7950971 | 0.79 | EGFR (0.39) | TDP1HSD17B10KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |