Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.59 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345734 | 0.85 | KMT2A (0.78) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL1030576 | 0.83 | CYP1A2 (0.65) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL30492996 | 0.83 | SMN1; SMN2 (0.68) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL2091191 | 0.83 | SMN1; SMN2 (0.67) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL1851780 | 0.83 | SMN1; SMN2 (0.68) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL2089273 | 0.83 | CYP1A2 (0.65) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL7760777 | 0.83 | CYP1A2 (0.65) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL2091189 | 0.82 | SMN1; SMN2 (0.61) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL7959628 | 0.81 | SMN1; SMN2 (0.66) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 | |
| SCHEMBL28190954 | 0.81 | IMPDH2 (0.63) | CYP1A2CYP2C19CYP2C9KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |