Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190983 | 0.89 | DHODH (0.43) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3131461 | 0.87 | PDE4A (0.47) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3131861 | 0.85 | PDK1 (0.43) | PDE4BPDK1 | |
| SCHEMBL1159028 | 0.85 | GRM2 (0.44) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3132313 | 0.85 | DHODH (0.40) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3132322 | 0.85 | DHODH (0.40) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3132226 | 0.84 | PDE4B (0.43) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3128750 | 0.84 | PDE4B (0.43) | DHODHPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1157700 | 0.84 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DNR3C2 | |
| SCHEMBL3126203 | 0.84 | NAPRT (0.46) | DHODHPDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |