SCHEMBL7946046

SCHEMBL7946046

CCC(O)(O)OC(=O)c1cccc(C(=O)OC(O)(O)CC)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
SLC7A5 Q01650 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.41
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946047 0.93 KMT2A (0.46) CYP1A2CYP2D6CYP2C19SLC7A5KMT2A
SCHEMBL3162941 0.87 CYP2D6 (0.57) CYP1A2CYP2D6CYP2C19ALDH1A1TSHR
SCHEMBL2788007 0.84 CYP1A2 (0.45) CYP1A2CYP2D6CYP2C19LOXL2ALDH1A1
SCHEMBL5368592 0.83 CYP1A2 (0.45) CYP1A2CYP2D6CYP2C19SLC7A5LOXL2
SCHEMBL5374679 0.81 CYP1A2 (0.47) CYP1A2CYP2D6CYP2C19SLC7A5LOXL2
SCHEMBL5373190 0.81 CYP1A2 (0.59) CYP1A2CYP2D6CYP2C19SLC7A5LOXL2
SCHEMBL4762257 0.79 SLC7A5 (0.45) CYP1A2CYP2D6CYP2C19SLC7A5LOXL2
SCHEMBL3096149 0.78 CYP1A2 (0.42) CYP1A2CYP2D6CYP2C19SLC7A5LOXL2
SCHEMBL2788009 0.78 ALDH1A1 (0.52) CYP1A2CYP2D6CYP2C19ALDH1A1TSHR
SCHEMBL16421103 0.77 SLC7A5 (0.52) CYP1A2CYP2D6CYP2C19SLC7A5LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379761-A1 Unsaturated polyesters and their preparation ARCO Chemical Technology, L.P. (US) 1990-08-01 EP claimed
US-4812553-A DIRECT ESTERIFICATION WITH UNSATURATED ANHYDRIDES OR DIACIDS ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-03-14 US claimed
WO-2001030879-A1 AROMATIC DIOL BASED URETHANEACRYLATES AND RESIN COMPOSITIONS CONTAINING THE SAME HAVING IMPROVED WATER AND/OR CHEMICAL RESISTANCE COOK COMPOSITES AND POLYMERS COMPANY (US) 2001-05-03 WO disclosed
EP-0379761-A1 Unsaturated polyesters and their preparation ARCO Chemical Technology, L.P. (US) 1990-08-01 EP disclosed
US-4812553-A DIRECT ESTERIFICATION WITH UNSATURATED ANHYDRIDES OR DIACIDS ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-03-14 US disclosed