SCHEMBL7946054

SCHEMBL7946054

O=C(O)c1cccc(C(=O)OCCC(O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.51
LMNA P02545 1/20 0.45
ALDH1A1 P00352 1/20 0.45
SLC7A5 Q01650 1/20 0.45
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
CA9 Q16790 1/20 0.42
APEX1 P27695 1/20 0.41
SERPINE1 P05121 1/20 0.41
FOLH1 Q04609 2/20 0.41
AKR1C3 P42330 1/20 0.41
ANPEP P15144 1/20 0.41
ENPEP Q07075 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946049 0.93 TDP1 (0.48) TDP1LMNAALDH1A1SLC7A5KMT2A
SCHEMBL29020000 0.91 TDP1 (0.57) TDP1LMNAALDH1A1SLC7A5FOLH1
SCHEMBL11558422 0.88 TDP1 (0.49) TDP1LMNAALDH1A1SLC7A5KMT2A
SCHEMBL9421257 0.86 TDP1 (0.62) TDP1LMNASLC7A5KMT2ACA12
SCHEMBL3096179 0.85 SLC7A5 (0.47) TDP1LMNAALDH1A1SLC7A5KMT2A
SCHEMBL27574211 0.84 TDP1 (0.60) TDP1LMNASLC7A5KMT2ACA12
SCHEMBL3162957 0.84 TDP1 (0.66) TDP1LMNAALDH1A1KMT2A
SCHEMBL209607 0.84 TDP1 (0.71) TDP1LMNAKMT2ACA12CA1
SCHEMBL29657345 0.84 TDP1 (0.41) TDP1LMNAALDH1A1SLC7A5KMT2A
SCHEMBL25193430 0.83 TDP1 (0.55) TDP1LMNAALDH1A1SLC7A5SERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0379761-A1 Unsaturated polyesters and their preparation ARCO Chemical Technology, L.P. (US) 1990-08-01 EP claimed
US-4812553-A DIRECT ESTERIFICATION WITH UNSATURATED ANHYDRIDES OR DIACIDS ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-03-14 US claimed
CN-119571493-A Preparation method of cationic-dyeable PET (polyethylene terephthalate) fiber and cationic-dyeable PET fiber 盛泰智慧(江门)环保科技有限公司 2025-03-07 CN disclosed
CN-119570051-A Preparation method and application of cationic dyeable PET 盛泰智慧(江门)环保科技有限公司 2025-03-07 CN disclosed
WO-2001030879-A1 AROMATIC DIOL BASED URETHANEACRYLATES AND RESIN COMPOSITIONS CONTAINING THE SAME HAVING IMPROVED WATER AND/OR CHEMICAL RESISTANCE COOK COMPOSITES AND POLYMERS COMPANY (US) 2001-05-03 WO disclosed
EP-0379761-A1 Unsaturated polyesters and their preparation ARCO Chemical Technology, L.P. (US) 1990-08-01 EP disclosed
US-4812553-A DIRECT ESTERIFICATION WITH UNSATURATED ANHYDRIDES OR DIACIDS ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-03-14 US disclosed