Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946054 | 0.93 | TDP1 (0.51) | TDP1LMNAALDH1A1SLC7A5SERPINE1 | |
| SCHEMBL29657345 | 0.91 | TDP1 (0.41) | TDP1LMNAALDH1A1SLC7A5SERPINE1 | |
| SCHEMBL25193430 | 0.89 | TDP1 (0.55) | TDP1LMNAALDH1A1SLC7A5SERPINE1 | |
| SCHEMBL3162957 | 0.87 | TDP1 (0.66) | TDP1LMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2788014 | 0.84 | MAPK1 (0.51) | TDP1LMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29020000 | 0.84 | TDP1 (0.57) | TDP1LMNAALDH1A1SLC7A5 | |
| SCHEMBL5371533 | 0.84 | KMT2A (0.58) | TDP1LMNAALDH1A1SLC7A5SERPINE1 | |
| SCHEMBL3096166 | 0.83 | SLC7A5 (0.48) | TDP1LMNAALDH1A1SLC7A5SERPINE1 | |
| SCHEMBL4762261 | 0.81 | ALDH1A1 (0.58) | TDP1ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL11558422 | 0.80 | TDP1 (0.49) | TDP1LMNAALDH1A1SLC7A5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379761-A1 | Unsaturated polyesters and their preparation | ARCO Chemical Technology, L.P. (US) | 1990-08-01 | — | — | EP | claimed |
| US-4812553-A | DIRECT ESTERIFICATION WITH UNSATURATED ANHYDRIDES OR DIACIDS | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1989-03-14 | — | — | US | claimed |
| WO-2001030879-A1 | AROMATIC DIOL BASED URETHANEACRYLATES AND RESIN COMPOSITIONS CONTAINING THE SAME HAVING IMPROVED WATER AND/OR CHEMICAL RESISTANCE | COOK COMPOSITES AND POLYMERS COMPANY (US) | 2001-05-03 | — | — | WO | disclosed |
| EP-0379761-A1 | Unsaturated polyesters and their preparation | ARCO Chemical Technology, L.P. (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4812553-A | DIRECT ESTERIFICATION WITH UNSATURATED ANHYDRIDES OR DIACIDS | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1989-03-14 | — | — | US | disclosed |