Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.65 |
| ▸ | CDK2 | P24941 | 4/20 | 0.65 |
| ▸ | TTK | P33981 | 4/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.65 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.65 |
| ▸ | LCK | P06239 | 4/20 | 0.65 |
| ▸ | CSF1R | P07333 | 4/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.65 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.65 |
| ▸ | KIT | P10721 | 4/20 | 0.65 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.65 |
| ▸ | FLT3 | P36888 | 3/20 | 0.65 |
| ▸ | CSNK1G1 | Q9HCP0 | 3/20 | 0.65 |
| ▸ | PLK4 | O00444 | 3/20 | 0.65 |
| ▸ | AURKA | O14965 | 3/20 | 0.65 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.65 |
| ▸ | CDK1 | P06493 | 3/20 | 0.65 |
| ▸ | LYN | P07948 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336855 | 0.85 | CDK2 (0.65) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL1296328 | 0.82 | TTK (0.65) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL14307405 | 0.79 | CDK2 (0.61) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL170980 | 0.79 | ALDH1A1 (1.00) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL29693577 | 0.79 | ALDH1A1 (1.00) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL29941507 | 0.79 | ALDH1A1 (1.00) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL18292352 | 0.79 | KMT2A (0.60) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL8342541 | 0.78 | CDK2 (0.60) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL14277252 | 0.78 | CDK2 (0.60) | KDRCDK2TTKDYRK1ACSNK1A1 | |
| SCHEMBL12102946 | 0.78 | CDK2 (0.56) | KDRCDK2TTKDYRK1ACSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039647-A2 | SELECTIVE INHIBITORS OF C-JUN N-TERMINAL KINASES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-04-08 | — | — | WO | disclosed |