SCHEMBL7946217

SCHEMBL7946217

CC(=O)OCCC(C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CC/C=C(\C)CCC=C(C)C

nearest known ligand 0.82

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.82
ALDH1A1 P00352 2/20 0.57
FNTA P49354 2/20 0.47
FNTB P49356 2/20 0.47
KMT2A Q03164 1/20 0.47
PTPN1 P18031 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10897554 1.00 ALOX15 (0.82) ALOX15ALDH1A1FNTAFNTBKMT2A
SCHEMBL7946220 1.00 ALOX15 (0.82) ALOX15ALDH1A1FNTAFNTBKMT2A
SCHEMBL10897556 1.00 ALOX15 (0.82) ALOX15ALDH1A1FNTAFNTBKMT2A
Geranyl Acetate SCHEMBL10583847 0.93 ALOX15 (0.75) ALOX15ALDH1A1FNTAFNTBPTPN1
Citronellyl Acetate SCHEMBL20912959 0.91 ALOX15 (1.00) ALOX15ALDH1A1PTPN1
Citronellyl Acetate SCHEMBL157075 0.91 ALOX15 (1.00) ALOX15ALDH1A1PTPN1
Citronellyl Acetate SCHEMBL1866109 0.91 ALOX15 (1.00) ALOX15ALDH1A1PTPN1
Citronellyl Acetate SCHEMBL2464823 0.87 ALOX15 (0.93) ALOX15ALDH1A1PTPN1
SCHEMBL15315224 0.85 ALOX15 (0.70) ALOX15ALDH1A1FNTAFNTBKMT2A
SCHEMBL31277576 0.85 ALOX15 (0.70) ALOX15ALDH1A1FNTAFNTBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288128-B1 β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound EISAI CO., LTD. (JP) 2001-09-11 US disclosed
US-6111131-A SUCH AS 3,7,11,15,19,23,27,31-OCTAMETHYL-2,6,10,14,18,22,26,30-DOTRIACONTAOCTAEN-1 -OL; USEFUL AS PROPHYLACTIC DRUG FOR IMMUNODEFICIENCY DISEASES AND INFECTIOUS DISEASES EISAI CO., LTD. (JP) 2000-08-29 US disclosed
US-5658958-A β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals EISAI CO., LTD. (JP) 1997-08-19 US disclosed
US-5280048-A Antiinfection agent EISAI CO., LTD. (JP) 1994-01-18 US disclosed
US-4624966-A β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound EISAI CO., LTD. (JP) 1986-11-25 US disclosed