Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765889 | 0.85 | POLB (0.49) | POLBALDH1A1MAPTL3MBTL1PTGDR | |
| SCHEMBL7946506 | 0.83 | POLB (0.44) | POLBALDH1A1MAPTL3MBTL1PTGDR | |
| SCHEMBL8765835 | 0.81 | POLB (0.49) | POLBALDH1A1MAPTL3MBTL1PTGDR | |
| SCHEMBL7946185 | 0.78 | VCAM1 (0.38) | ALDH1A1MAPTCA2CA1CA9 | |
| SCHEMBL8766839 | 0.77 | POLB (0.42) | POLBALDH1A1MAPTL3MBTL1PTGDR | |
| SCHEMBL16307388 | 0.77 | PSEN1 (0.41) | ALDH1A1CA2CA1CA9CA12 | |
| SCHEMBL14420868 | 0.77 | CA1 (0.36) | ALDH1A1MAPTCA2CA1CA9 | |
| SCHEMBL8121313 | 0.77 | CA1 (0.36) | ALDH1A1MAPTCA2CA1CA9 | |
| SCHEMBL9822418 | 0.74 | IDO1 (0.46) | ALDH1A1MAPTL3MBTL1PTGDRCA2 | |
| SCHEMBL249746 | 0.74 | IDO1 (0.54) | POLBALDH1A1MAPTL3MBTL1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258984-B1 | CHLORINATION OF P-ALKYLBENZENESULFONYL CHLORIDE | CLARIANT GMBH (DE) | 2001-07-10 | — | — | US | claimed |
| EP-0571405-B1 | Process for preparing 4-alkylsulfonyl-1-alkyl-2-chlorobenzenes and intermediates | HOECHST AG (DE) | 1996-05-01 | — | — | EP | claimed |
| EP-0619303-B1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |
| EP-0619303-A1 | 4-alkyl-3-chloro-benzenesulfinic acids, 4-alkyl-3-chloro-benzenesulfonic acids, 4-alkyl-3-chloro-alkylsulfonylbenzenes and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |