Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 10/20 | 0.52 |
| ▸ | RAB9A | P51151 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947593 | 0.86 | LMNA (0.63) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7946507 | 0.84 | KMT2A (0.53) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7945565 | 0.79 | KMT2A (0.50) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7948467 | 0.79 | KMT2A (0.50) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7939190 | 0.76 | KMT2A (0.49) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7945583 | 0.76 | KMT2A (0.49) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7947599 | 0.75 | MEN1 (0.55) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL7948446 | 0.74 | KMT2A (0.47) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL6819568 | 0.74 | KMT2A (0.64) | KMT2ATDP1MEN1LMNANPC1 | |
| SCHEMBL30739608 | 0.72 | LMNA (1.00) | KMT2ATDP1MEN1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |