SCHEMBL7946487

SCHEMBL7946487

C=CC(O)C=CC=CC/C=C\CCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
MAPT P10636 1/20 0.55
OXER1 Q8TDS5 1/20 0.53
LTB4R2 Q9NPC1 1/20 0.51
FAAH O00519 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3004869 0.83 PPARG (0.43) ALOX5MAPTOXER1LTB4R2FAAH
SCHEMBL3004862 0.83 PPARG (0.43) ALOX5MAPTOXER1LTB4R2FAAH
SCHEMBL8418621 0.81 ABCG2 (0.60) MAPT
SCHEMBL8418619 0.81 ABCG2 (0.60) MAPT
SCHEMBL8263225 0.79 LTB4R2 (0.76) ALOX5MAPTLTB4R2FAAH
SCHEMBL13533650 0.79 LTB4R2 (0.76) ALOX5MAPTLTB4R2FAAH
SCHEMBL13149074 0.79 ALOX5 (0.67) ALOX5MAPTOXER1LTB4R2FAAH
SCHEMBL13148476 0.78 LTB4R2 (0.78) ALOX5MAPTLTB4R2FAAH
SCHEMBL10482052 0.78 ALOX5 (0.78) ALOX5MAPTOXER1LTB4R2FAAH
SCHEMBL27153686 0.77 TRPV1 (0.59) OXER1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001013931-A1 HYPERTENSION-TREATMENT AND CHOLESTEROL-DEPRESSANT COMPOSITION COMPRISING EXTRACT FROM MIXTURE OF PANAX NOTOGINSENG AND SALVIA MILTIORRHIZA AND METHOD OF PREPARING THE SAME MEDVILL CO., LTD. (KR) 2001-03-01 WO disclosed