SCHEMBL7946491

SCHEMBL7946491

OC12CC1=Cc1ccccc12

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
PDK2 Q15119 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
UBE2N P61088 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4608440 0.70 ESR1 (0.38) ESR1ESR2PDK2
SCHEMBL30040937 0.70 ESR1 (0.38) ESR1ESR2PDK2
SCHEMBL4147103 0.66
SCHEMBL17627642 0.64 GAA (0.35) ESR1ESR2MEN1MAPTKMT2A
SCHEMBL7652059 0.64 MAOB (0.37) TP53TSHRMAPK1
SCHEMBL2731093 0.63 ADORA3 (0.41) PDK2ADORA3MEN1KMT2A
SCHEMBL14410910 0.62 ESR1 (0.36) ESR1ESR2PDK2
SCHEMBL7941719 0.61 PDK2 (0.33) PDK2TSHR
Hydrochloric Acid SCHEMBL2780496 0.60 MEN1 (0.30) MEN1TP53MAPTTSHRMAPK1
Hydrochloric Acid SCHEMBL1129489 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271194-B1 PERFUME INTERNATIONAL FLAVORS & FRAGRANCES INC. 2001-08-07 US disclosed