Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trans-Phytol SCHEMBL1254535 | 0.90 | PTPN1 (0.93) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL8079351 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| Trans-Phytol SCHEMBL17962948 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL8079352 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL8079353 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| Trans-Phytol SCHEMBL14763835 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| Trans-Phytol SCHEMBL22784 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL4718132 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| Trans-Phytol SCHEMBL16367020 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A | |
| SCHEMBL8070052 | 0.90 | PTPN1 (1.00) | PTPN1PTGS1PDE4ASNCAPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262029-B1 | TRITERPENE AGLYCONE CORE SUBSTITUTED AT POSITIONS 3 AND 28 WITH A MONOSACCHARIDE OR AN OLIGOSACCHARIDE WHICH CAN BE THE SAME OR DIFFERENT, AND HAVING AN ALDEHYDE GROUP ATTACHED TO THE CORE, PREFERABLY AT THE 4-POSITION. | GALENICA PHARMACEUTICALS, INC. | 2001-07-17 | — | — | US | disclosed |
| WO-2000009075-A2 | CHEMICALLY MODIFIED SAPONINS AND THE USE THEREOF AS ADJUVANTS | GALENICA PHARMACEUTICALS, INC. (US) | 2000-02-24 | — | — | WO | disclosed |