SCHEMBL794673

SCHEMBL794673

CC(C)=CCCC(C)=CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 1.00
ATM Q13315 1/20 1.00
POLB P06746 1/20 0.67
KDM1A O60341 1/20 0.58
KMT2A Q03164 4/20 0.56
FNTA P49354 6/20 0.55
FNTB P49356 6/20 0.55
ALDH1A1 P00352 3/20 0.54
ALOX15 P16050 3/20 0.52
MEN1 O00255 3/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 3/20 0.50
TRPA1 O75762 1/20 0.50
UGT1A1 P22309 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29526077 1.00 KDM4E (1.00) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL358253 1.00 KDM4E (1.00) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL310619 1.00 KDM4E (1.00) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL10566443 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL9366045 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL1470207 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A
Geranylgeranoic Acid SCHEMBL10781543 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL7943006 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A
SCHEMBL7943004 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A
Geranylgeranoic Acid SCHEMBL10405196 0.96 KDM4E (0.92) KDM4EATMPOLBKDM1AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163333-A1 METHODS AND SYSTEMS FOR DISPERSING CATALYST PRECURSORS INTO HYDROCARBON FEEDSTOCKS TO FORM CONDITIONED FEEDSTOCKS CONTAINNG NONPETROLEUM-DERIVED HYDROCARBONS HYDROCARBON TECHNOLOGY & INNOVATION, LLC 2025-05-22 US claimed
WO-2025106443-A1 METHODS AND SYSTEMS FOR DISPERSING CATALYST PRECURSORS INTO HYDROCARBON FEEDSTOCKS TO FORM CONDITIONED FEEDSTOCKS CONTAINING NONPETROLEUM-DERIVED HYDROCARBONS HYDROCARBON TECHNOLOGY & INNOVATION, LLC (US) 2025-05-22 WO claimed
US-12275896-B2 Catalytic hydrotreating of feedstocks NESTE OYJ (FI) 2025-04-15 US claimed
CN-117838801-A Orchid composite extract and its use in preparing composition with anti-depression effect 福建农林大学 2024-04-09 CN claimed
EP-4219663-A2 A PROCESS FOR MANUFACTURING CATALYTIC MICROPARTICLES Neste Oyj (FI) 2023-08-02 EP claimed
CN-115777797-A Processing method of Zijuan white tea for green removing process 广西南亚热带农业科学研究所 2023-03-14 CN claimed
US-20230069301-A1 CATALYTIC HYDROTREATING OF FEEDSTOCKS NESTE OYJ (FI) 2023-03-02 US claimed
EP-4081623-A1 CATALYTIC HYDROTREATING OF FEEDSTOCKS Neste Oyj (FI) 2022-11-02 EP claimed
CN-110621654-B TRPV1 modulator compounds 安塔尔遗传学公司 2022-11-01 CN claimed
CN-114846121-A Catalytic hydrotreating of feedstock 耐思特公司 2022-08-02 CN claimed
WO-2012113891-A1 USE OF POLYAMINOISOPRENYL DERIVATIVES IN ANTIBIOTIC OR ANTISEPTIC TREATMENT UNIVERSITE D'AIX-MARSEILLE (FR) 2012-08-30 WO claimed
WO-2012034232-A1 TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS NEUROQUEST INC. (CA) 2012-03-22 WO claimed
US-20070270474-A1 drugs have beta-amyloid peptide production inhibitory activity, such as 2-(2-benzo[b]thiophen-4-yl-acetylamino)-N-(5-phenyl-2H-pyrazol-3-yl)-propionamide, useful for treatment of Alzheimer's disease and Down's Syndrome PFIZER INC. 2007-11-22 US claimed
US-7238721-B2 Pyrazole compounds for treatment of neurodegenerative disorders PFIZER INC (US) 2007-07-03 US claimed
EP-1551809-A1 PYRAZOLE COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISORDERS Pfizer Products Inc. (US) 2005-07-13 EP claimed
US-20040142997-A1 Pyrazole compounds for treatment of neurodegenerative disorders PFIZER INC. 2004-07-22 US claimed
WO-2004033434-A1 PYRAZOLE COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PRODUCTS INC. (US) 2004-04-22 WO claimed
CN-1096292-C Method for preparing bimetallic ruthenium/tin catalyst PHODIA CHIMIE (FR) 2002-12-18 CN claimed
US-4115417-A ENANTIOSELECTIVITY HOFFMANN-LA ROCHE INC. (US) 1978-09-19 US claimed
US-3971827-A Manufacture of poly-(cis)-isoprenols G. D. SEARLE & CO. (US) 1976-07-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142997-A1 Pyrazole compounds for treatment of neurodegenerative disorders APP, PARK7, BACE1 KDM4E 4222/4885ATM 2268/4885POLB 3819/4885
US-20070270474-A1 drugs have beta-amyloid peptide production inhibitory activity, such as 2-(2-benzo[b]thiophen-4-yl-acetylamino)-N-(5-phenyl-2H-pyrazol-3-yl)-propionamide, useful for treatment of Alzheimer's disease and Down's Syndrome APP, BACE1, PSEN1 KDM4E 3471/4885ATM 2458/4885POLB 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.