Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551899 | 0.90 | SMN1; SMN2 (0.70) | NPSR1SMN1; SMN2LMNAUSP2TLR8 | |
| SCHEMBL7946547 | 0.84 | NPSR1 (0.68) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 | |
| SCHEMBL230840 | 0.80 | POLB (0.58) | NPSR1SMN1; SMN2LMNAUSP2CYP1A2 | |
| SCHEMBL18250273 | 0.79 | LMNA (0.67) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 | |
| SCHEMBL21540458 | 0.78 | NPSR1 (0.63) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 | |
| SCHEMBL12915261 | 0.76 | NPSR1 (0.61) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 | |
| SCHEMBL30134160 | 0.76 | SMN1; SMN2 (0.73) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 | |
| SCHEMBL13497652 | 0.76 | NPSR1 (0.61) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 | |
| SCHEMBL10823939 | 0.76 | NPSR1 (1.00) | NPSR1SMN1; SMN2LMNAUSP2CYP1A2 | |
| SCHEMBL14600592 | 0.75 | NPSR1 (0.60) | NPSR1SMN1; SMN2LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180788-B1 | METAL COMPLEXES FOR CATALYSTS WITH COPPER, SILVER OR GOLD | EXXON RESEARCH AND ENGINEERING COMPANY | 2001-01-30 | — | — | US | disclosed |