Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | SI | P14410 | 1/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.59 |
| ▸ | PPIB | P23284 | 1/20 | 0.59 |
| ▸ | PPIA | P62937 | 1/20 | 0.59 |
| ▸ | PPIG | Q13427 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16223208 | 0.91 | PPID (0.60) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL14467616 | 0.89 | PPID (0.54) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL8144848 | 0.89 | GAA (0.55) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL8144854 | 0.89 | GAA (0.55) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL7748210 | 0.88 | PPID (0.53) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL12341387 | 0.88 | GAA (0.59) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL12341367 | 0.88 | GAA (0.59) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL3042437 | 0.87 | GAA (0.53) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL3267070 | 0.86 | PPID (0.52) | PPIDGAAMGAMSIMGAM2 | |
| SCHEMBL20604079 | 0.86 | PPID (0.51) | PPIDGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258840-B1 | ANTITUMOR AGENTS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF KINASES | COBRA THERAPEUTICS LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |
| EP-0912541-A1 | ANALOGUES OR DERIVATIVES OF QUERCETIN (PRODRUGS) | Cobra Therapeutics Limited (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997049693-A1 | ANALOGUES OR DERIVATIVES OF QUERCETIN (PRODRUGS) | COBRA THERAPEUTICS LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |
| US-4328027-A | Di-triethylamine salt of N,N'-bis-carboethoxymethyl-N,N'-bis-phosphonomethylurea and its use as a plant growth regulator | STAUFFER CHEMICAL COMPANY (US) | 1982-05-04 | — | — | US | disclosed |