Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PPID | Q08752 | 4/20 | 0.53 |
| ▸ | PPIB | P23284 | 1/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.53 |
| ▸ | PPIG | Q13427 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946756 | 0.87 | PPID (0.62) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL8144854 | 0.81 | GAA (0.55) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL8144848 | 0.81 | GAA (0.55) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL10470968 | 0.80 | GAA (0.50) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL16223208 | 0.79 | PPID (0.60) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL3309951 | 0.78 | GAA (0.57) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL182292 | 0.78 | — | — | |
| SCHEMBL7089973 | 0.78 | GAA (0.61) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL4220135 | 0.78 | PPID (0.54) | GAAPPIDPPIBPPIAPPIG | |
| SCHEMBL14467616 | 0.78 | PPID (0.54) | GAAPPIDPPIBPPIAPPIG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708370-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2017-07-18 | — | — | US | disclosed |
| EP-2160404-B1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | VALORISATION RECHERCHE LTD PARTNERSHIP (CA) | 2016-08-24 | — | — | EP | disclosed |
| US-20150329591-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2015-11-19 | — | — | US | disclosed |
| US-9115171-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2015-08-25 | — | — | US | disclosed |
| US-20130203686-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | INSERM (FR) | 2013-08-08 | — | — | US | disclosed |
| US-8435954-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2013-05-07 | — | — | US | disclosed |
| US-20100210566-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2010-08-19 | — | — | US | disclosed |
| EP-2160404-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008154738-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329591-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | MSR1, ASGR1, LDLR | GAA 165/4885PPID 4556/4885PPIB 3019/4885 |
| US-20130203686-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | MSR1, ASGR1, SCARB1 | GAA 234/4885PPID 4622/4885PPIB 3243/4885 |
| US-20100210566-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | GHRHR, GHSR, GNRHR | GAA 401/4885PPID 4583/4885PPIB 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.