Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830463 | 0.89 | MTOR (0.70) | MTORCYP3A4 | |
| SCHEMBL7936477 | 0.88 | MTOR (0.64) | MTORCYP3A4 | |
| SCHEMBL7943828 | 0.87 | MTOR (0.58) | MTORCYP3A4 | |
| SCHEMBL7944571 | 0.84 | MTOR (0.56) | MTOR | |
| SCHEMBL7946429 | 0.84 | MTOR (0.56) | MTOR | |
| SCHEMBL7943773 | 0.82 | MTOR (0.59) | MTOR | |
| SCHEMBL1834920 | 0.81 | MTOR (0.72) | MTORCYP3A4 | |
| SCHEMBL1832966 | 0.81 | MTOR (0.77) | MTORCYP3A4 | |
| SCHEMBL7946877 | 0.79 | MTOR (0.53) | MTORCYP3A4 | |
| SCHEMBL7935973 | 0.78 | MTOR (0.54) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |