Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.45 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830938 | 0.89 | MTOR (0.70) | MTORCYP3A4RPTORMLST8 | |
| SCHEMBL7936477 | 0.88 | MTOR (0.64) | MTORCYP3A4 | |
| SCHEMBL1832966 | 0.81 | MTOR (0.77) | MTORCYP3A4RPTORMLST8 | |
| SCHEMBL7946429 | 0.81 | MTOR (0.56) | MTORRPTORMLST8 | |
| SCHEMBL7946867 | 0.79 | MTOR (0.54) | MTORCYP3A4 | |
| SCHEMBL7944571 | 0.79 | MTOR (0.56) | MTORRPTORMLST8 | |
| SCHEMBL7943773 | 0.79 | MTOR (0.59) | MTOR | |
| SCHEMBL7935973 | 0.79 | MTOR (0.54) | MTORRPTORMLST8 | |
| SCHEMBL7944090 | 0.78 | MTOR (0.70) | MTORCYP3A4RPTORMLST8 | |
| SCHEMBL1833231 | 0.78 | MTOR (0.80) | MTORCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |