Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27342827 | 0.88 | PNMT (0.50) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL5358644 | 0.85 | PNMT (0.48) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL7638494 | 0.85 | PNMT (0.48) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7945368 | 0.83 | PNMT (0.48) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7195192 | 0.78 | PNMT (0.72) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL3994174 | 0.77 | PNMT (0.54) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7607164 | 0.77 | PNMT (0.70) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL7606240 | 0.77 | PNMT (0.70) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL7646508 | 0.76 | PNMT (0.40) | PNMTDRD2DRD4DRD3NPC1 | |
| SCHEMBL27364427 | 0.76 | PNMT (0.47) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |