Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.46 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xyloquinone SCHEMBL49964 | 0.82 | PLK1 (0.60) | PLK1PLK2EEF2KSTAT3MAPT | |
| SCHEMBL169616 | 0.82 | KDM4E (0.43) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL28875633 | 0.82 | KDM4E (0.43) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL28758922 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL28391346 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| Potassium SCHEMBL29990441 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| Potassium SCHEMBL31397834 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL11135771 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| SCHEMBL11411413 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E | |
| Lithium SCHEMBL30194867 | 0.78 | KDM4E (0.42) | MAPTALDH1A1KMT2AMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731945-B2 | Redox-active compounds and uses thereof | CMBLU ENERGY AG (DE) | 2023-08-22 | — | — | US | disclosed |
| CN-113528563-B | Preparation method and application of visual biosensor synthesized by using explosive molecule degradation genes | 青岛农业大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-113528563-B | Preparation method and application of visual biosensor synthesized by using explosive molecule degradation genes | 青岛农业大学 | 2023-06-20 | — | — | CN | disclosed |
| EP-3842420-B1 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS LLC (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-113481114-B | Yeast cell surface display technology-based explosive visualization biosensor and preparation method and application thereof | 青岛农业大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-113481114-B | Yeast cell surface display technology-based explosive visualization biosensor and preparation method and application thereof | 青岛农业大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-110818553-B | Anti-inflammatory compound of desmodium parvifolium and preparation method thereof | 青海师范大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113528563-A | Preparation method and application of visual biosensor synthesized by using explosive molecule degradation genes | 青岛农业大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-113528412-A | Explosive visualization biosensor based on escherichia coli cell surface display technology and preparation method and application thereof | 青岛农业大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-113528412-A | Explosive visualization biosensor based on escherichia coli cell surface display technology and preparation method and application thereof | 青岛农业大学 | 2021-10-22 | — | — | CN | disclosed |
| US-20190218531-A1 | TWO PHASE SUSTAINABLE PHOTOPRODUCTION VIA CO-CULTIVATION OF ENCAPSULATED, CARBOHYDRATE-PRODUCING CYANOBACTERIA | NATIONAL SCIENCE FOUNDATION | 2019-07-18 | — | — | US | disclosed |
| US-9777024-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2017-10-03 | — | — | US | disclosed |
| US-20160137672-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2016-05-19 | — | — | US | disclosed |
| US-9221843-B2 | Heteroaryl inhibitors of PDE4 | Tetra Discovery Partners, LLC (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150119362-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC | 2015-04-30 | — | — | US | disclosed |
| WO-2014066659-A9 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS, LLC. (US) | 2015-02-12 | — | — | WO | disclosed |
| US-6248580-B1 | ADDING MIXED CULTURE OF BATERIA WITH DEGRADE AND USE 2,4-DINITROTOLUENE AND 2,6-DINITROTOLUENE AS CARBON AND NITROGEN SOURCE, THEN PRODUCING AND MAINTAINING AEROBIC CONDITIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2001-06-19 | — | — | US | disclosed |
| EP-0330517-B2 | Method, system and devices for the assay and detection of biochemical molecules | SOLARCARE TECHNOLOGIES CORP (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5126247-A | For enzymatic colorimatic measurement of presence or concentration of analytes in samples of animal fluids; medical diagnosis | ENZYMATICS, INC. (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0330517-A2 | Method, system and devices for the assay and detection of biochemical molecules | SOLARCARE TECHNOLOGIES CORPORATION (US) | 1989-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119362-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | PLK1 3024/4885PLK2 2430/4885EEF2K 1768/4885 |
| US-11731945-B2 | Redox-active compounds and uses thereof | NOX4, NQO1, GPX1 | PLK1 1719/4885PLK2 1748/4885EEF2K 4295/4885 |
| US-20160137672-A1 | HETEROARYL INHIBITORS OF PDE4 | PDE4A, PDE4B, PDE4C | PLK1 3024/4885PLK2 2430/4885EEF2K 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.