Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL2157202 | 0.95 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL11431222 | 0.95 | — | — | |
| Nitric Acid SCHEMBL7947036 | 0.95 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL11438732 | 0.95 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL787462 | 0.95 | — | — | |
| Nitric Acid SCHEMBL646248 | 0.95 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL15408318 | 0.91 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL15121484 | 0.91 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL7147203 | 0.91 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL4824217 | 0.91 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180731-B1 | COMPRISING A PHILLIPS CATALYST (I), A SOLID DIFFERENT FROM (I) THAT COMPRISES A COMPONENT DERIVED FROM METALLOCENE COMPLEXES OF GIVEN FORMULA, AND AN ORGANOMETALLIC COMPONENT SELECTED FROM GROUPS 1A, 2A, 3A, AND 2B OF THE PERIODIC TABLE | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-30 | — | — | US | disclosed |
| US-4376851-A | HIGH DENSITY, HEAT RESISTANCE POLYPROPYLENE | PHILLIPS PETROLEUM COMPANY (US) | 1983-03-15 | — | — | US | disclosed |
| US-4342854-A | PRODUCTION OF 4-METHYL -1-PENTENE BY CATALYTIC DIMERIZATION OF PROPYLENE, AND POLYMERIZATION OF 4-METHYL -1-PENTENE IN THE PRESENCE OF A CROMIUM (VI) OXIDE CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1982-08-03 | — | — | US | disclosed |